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Jun 28th, 2026

BUS TICKETS FROM IQUIQUE TO SANTA CRUZ

Buses from Iquique to Santa Cruz depart every day at 10:30 AM from the Iquique Bus Terminal (Terminal Rodoviario) located on Patricio Lynch Street S/N. Bus Fer offers a direct service to Santa Cruz, handling customs procedures in Pisiga and completing the journey in about 27 hours. Buses arrive at the Santa Cruz Bimodal Terminal on Avenida Intermodal. Travelers may also choose a connection in Cochabamba, changing buses at the Cochabamba Bus Terminal.

  • HOW TO TRAVEL FROM IQUIQUE TO SANTA CRUZ BY BUS?

    TicketsBolivia offers two options for traveling by bus on this route: Direct Trip: Morning departure with Bus Fer in comfortable "Bus Cama" units. Arrives the next day with only a brief technical stop at Pisiga (no bus change). Trip with Layover: Connect via Cochabamba, where you will switch buses. Ride with Tour Bus Vincent or Bus Fer for the first leg, and complete your journey to Santa Cruz with Trans Copacabana 1 MEM or Trans Copacabana SA.

  • WHAT TO DO IN SANTA CRUZ?

    Santa Cruz offers unforgettable experiences that blend nature, culture, and history. 1-day tour to Amboró National Park takes visitors through lush forests, waterfalls, and scenic trails rich in wildlife. For a deeper cultural journey. 3-day tour of the Jesuit Missions of Chiquitos explores UNESCO-listed towns, colonial churches, museums, and artisan workshops. Both options showcase the unique heritage and landscapes of eastern Bolivia.

Join 100,000+ travelers trusting Tickets Bolivia! For over a decade, we’ve offered the best routes and competitive prices. Book securely with dedicated customer support before and after your purchase. Need to change or cancel? Enjoy flexible policies and direct assistance every step of the way. Secure your seat today at the best price on a safe, transparent platform!

IQUIQUE TO SANTA CRUZ SCHEDULE, COMPANIES AND PRICES

Bus Company Departure Arrival Type of bus Price from  
Bus Fer 10:30 AM 14:00 PM Lie-flat bus $us 131

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  • Trip duration: 27 hours
  • Distance: 1185.0km
  • Price range: from $131 USD to $131 USD
    • Departure bus stop in Iquique
      Patricio Linch street S/N
    • Arrival bus terminal in Santa Cruz
      Intermodal avenue

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