The trip from Santa Cruz to Yacuiba by bus takes around 10 hours, covering a distance of 548 km. In order to take the bus you must go to the bimodal terminal in Santa Cruz, located on Intermodal avenue. The buses leave every day at night and arrive in Yacuiba at the bus station located on San Martin avenue early in the morning. There is also a train which leaves from Santa Cruz every Friday at 5:00pm. The journey in train takes 17 hours.
Santa Cruz is the most important Bolivian city in the
south, and Yacuiba is a small city on the border between Argentina and Bolivia,
which makes it a high-traffic destination for travelers of both countries, as
well as an important center of economic activity. On the other side of the
border is the Argentinian town of Salvador Mazza. It is one of the most
important border crossings between Argentina and Bolivia, and therefore it is
buzzing with commerce and travelers year-round.
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